SIM&CURE
Sim&Cure – Empowering Precision in Neurovascular Treatment
Sim&Cure is a MedTech company based in France, specializing in the development of digital solutions to assist physicians in the planning and personalization of endovascular treatment for cerebral aneurysms. Founded in 2014, Sim&Cure combines advanced simulation technology with clinical expertise to improve patient outcomes and streamline decision-making in neurointervention.
Our flagship solution, Sim&Size™, is a CE-marked and FDA cleared software platform that enables physicians to simulate the deployment of neurovascular devices prior to intervention. By leveraging patient-specific 3D imaging and device modeling, Sim&Size™ supports treatment planning with greater accuracy, consistency, and confidence—helping clinicians make better-informed decisions tailored to each individual case.
Sim&Cure works closely with healthcare professionals, researchers, and industry partners to ensure that innovation is rooted in real-world clinical needs. Our technology is currently used in 400+ hospitals across more than 45 countries, contributing to the treatment of over 30,000 patients.
Beyond product development, Sim&Cure is also actively involved in clinical research, training initiatives, and collaborative projects that push the boundaries of digital health in neurointervention. Our team includes biomedical engineers, clinical experts, and data scientists who are passionate about bringing meaningful innovation to the field.
With a strong focus on safety, usability, and integration with existing clinical workflows, Sim&Cure is committed to shaping the future of minimally invasive treatment through digital precision.
For more information, visit: www.sim-and-cure.com
Role in the project
As a key partner in the SHERPA project, Sim&Cure brings its expertise in patient-specific simulation to enhance neurointerventional care.
We focus on two main areas:
- Advanced 3D Visualization & Planning – Supporting the evaluation and integration of novel 3D technologies, with enhanced incorporation of Sim&Size™ into operating rooms to optimize preoperative workflows.
- Predictive Modeling & Clinical Validation – Contributing to a 2,000-patient study to evaluate Sim&Predict’s role in treatment planning, efficiency, and outcomes. Sim&Cure also leads clinical trials to assess the safety and impact of these innovations on real-world workflows.
Team
Christophe Chnafa
Christophe Chnafa serves as Chief Innovation and Strategy Officer at Sim&Cure, where he oversees the company’s Research & Development, Product, Engineering, Regulatory & Quality Affairs, and Clinical & Medical Affairs. activities. With a PhD in applied mathematics and a strong background in computational modeling and medical technologies, Christophe drives strategic innovation across all departments. His role bridges scientific research, technical excellence, and product strategy to ensure that Sim&Cure delivers safe, effective, and clinically meaningful solutions for neurovascular treatment planning. He plays a key role in aligning long-term vision with operational execution to scale impactful digital health innovations in clinical practice.
Sophie Bruge
As Director of Research & Development at Sim&Cure, Sophie Bruge leads the scientific and technical advancements that power the company’s simulation-based planning technologies. With a PhD in applied Mathematics for medical image processing and a strong foundation in algorithm developments, she plays a key role in designing and validating innovative digital solutions that support clinical decision-making. Sophie works closely with cross-disciplinary teams to ensure that Sim&Cure’s products are grounded in scientific rigor and tailored to physicians’ real-world needs. She focuses on translating complex research into robust, clinically relevant tools that help shape the future of image-based medical planning.
Amandine René
Amandine René leads the Clinical and Medical Affairs department at Sim&Cure, where she is responsible for clinical strategy, evidence generation, and physician engagement. With a PhD focused on the clinical evaluation and validation of Software as a Medical Device (SaMD), and extensive experience in the digital health and medical device industry, Amandine brings deep expertise in clinical research and safety management. Her work ensures that Sim&Cure’s solutions meet the highest standards of safety, performance, and clinical relevance. Passionate about evidence-based innovation, she focuses on delivering robust data that supports the safe and efficient integration of simulation technologies into everyday clinical practice—always putting patient safety first.
